Interstate 4 eastbound in Seminole County is shut down near mile marker 102 in Sanford due to heavy police activity involving a possible explosive in a truck, according to News6. Motorists are advised to seek alternate routes.

According to witnesses, multiple roads in the area are closed, and law enforcement is actively on scene. Florida 511 reports that I-4 east is blocked near the old Seminole Towne Center.
Traffic cameras show both the Florida Highway Patrol and Seminole County Sheriff’s Office responding.
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Official statements
Seminole County wrote on X, “Motorists please be advised that all eastbound lanes of Interstate 4 (I-4) are closed near mile marker 102, close to SR 46 in Sanford. Please seek alternate routes and expect delays.”
Sanford Police added, “Due to an incident being worked by the Florida Highway Patrol on Interstate 4 ( I-4), drivers in the City of Sanford should expect traffic congestion on roadways near I-4 and SR 46, and I-4 and H.E. Thomas Pkwy. Other areas are also being affected such as Monroe Road and W. Seminole Blvd. Please drive with caution and use alternate routes when possible. Once the Florida Highway Patrol concludes their incident, traffic will return to regular flow.”
In an email to FOX 35, Florida Highway Patrol (FHP) spokesperson Lt. Tara Crescenzi said that FHP was “advised that there may be an explosive on the truck.”
“In an abundance of caution, we requested resources from the Seminole County Sheriff’s Office to clear the vehicle. There is roadblock for the eastbound lanes of I-4 and the ramps in the area,” she told the outlet.
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Witness reports
Several residents shared updates on social media.
One witness wrote on X, “Anyone know what’s going on eastbound i4 by Seminole towne center mall? Roads closed, biohazard trucks 40 cop cars.”
Another reported, “Interstate 4 eastbound is shut down.”